Hesperidin molecule 

Hesperidin is a flavanone glycoside (bioflavonoid) existing extensively in the peel and membranes of citrus fruits with novel pharmaceutical properties.

Studies by Zhu and colleagues have demonstrated hesperidin's potent ability to inhibit melanin synthesis without cytotoxicity. This work found dose-dependent inhibition of tyrosinase activity (vs control) of hesperidin in melanoma B16 cells and human primary melanocytes.

In addition, hesperidin was found to protect against UVA-induced damage of fibroblasts and oxidative damage of collagen.

Thus, hesperidin offers potential skin-lightening benefits, including improved overall skin tone and antiyellowing effects.